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G. B. Golubitskii, V. M. Ivanov
Quantitative
analyse of tablets and syrup “Codelac bronkho” by high pressure liquid
chromatography methods
Abstract
A procedure
was proposed for the quantitative analysis of the new original tablets and
syrup “Codelac bronkho”. The components of the pills were separated in 6
minutes with effective peak resolution. The procedure was used for the analysis
of a preproduction samples of the tablets. The results correspond to the
normative documentation merits and the technological loadings. Model solutions
containing all the active principles and additives of the drugs were analyzed,
and the performance characteristics of both procedures were calculated. Two
versions of analysis in isocratic and gradient modes were proposed for the
syrup. Both procedures afford reliable analytical results; however, the
isocratic version is technically simpler and more preferable for product
control in commercial production.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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