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N. Yu. Budanova, Ye. N. Shapovalova, O. A. Shpigun
Looking into the
Possibility of Using of Chitosan in Capillary Electrophoresis
Abstract
Some possibilities for
application in capillary electrophoresis of low-molecular water-soluble chitosan
as chiral selector for enantioseparation of aromatic acids and for the
modification of fused-silica capillary surface are discussed. The chitosan
coated capillary performance is demonstrated by fast separation of aromatic
acids. The migration times of acids depend slightly on chitosan concentration. The
chitosan coated capillary is used for chiral separations of acids with
2-hydroxypropyl-b-cyclodextrin, the enantioseparation conditions of
2-phenylpropionic acid are optimized.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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