M. V. Shunina, M. G. Chernobrovkin, A. V. Bashilov, E. N. Shapovalova, O. A. Shpigun The influence of Temperature and Microwave Radiation on the Preparation of Some Amino Acids Derivatives Abstract It was investigated three ways of the preparation of dansyl chloride (5 – dimethylamino – naphthalenesulfonic acid chloride) derivatives of amino acids: under room temperature, under heating the reactionary mixture upon 40°C and under the influence of microwave-field upon 40°C. It was shown that heating reactionary mixture to 40°C and action microwave oven do not improve the condition of the preparation dansyl chloride derivatives of amino acids essentially. It was found that carrying out the reaction of derivatization is most effectively upon room condition. Optimum conditions of the preparation of dansyl chloride derivatives were chosen.
Copyright (C) Chemistry Dept., Moscow State University, 2002 |
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