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L. N. Grushevskaya, M. V. Gusev, E. V. Blinskaya, N. V. Tikhonova, A. I. Marachova, L. M. Gaevaya, N. I. Avdyunina, K. V. Alekseev, B. M. Pyatin, S. E. Kondakov

Methods of identification of the formulation parameters for dilept tablets, innovative neuroleptic drug

Abstract

The technological characteristics of the Dilept substance were studied, the appropriate excipients and formulation parameters for Dilept tablets were selected. Identification, determination of related substances, uniformity of dosage units and assay tests were performed by HPLC. The quantitative analysis of Dilept in tablets for dissolution test was conducted by UV-spectrophotometry. Dilept tablets were shown to be stable during storage, a shelf-life of two years has been declared.
Key words: dilept, tablets, formulation parameters, analytical methods, HPLC.
Moscow University Chemistry Bulletin.
2013, Vol. 54, No. 5, P. 288
   

Copyright (C) Chemistry Dept., Moscow State University, 2002
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